Catalytic Asymmetric Synthesis of Highly Substituted Pyrrolizidines.
نویسندگان
چکیده
A catalytic asymmetric double (1,3)-dipolar cycloaddition reaction has been developed. Using a chiral silver catalyst, enantioenriched pyrrolizidines can be prepared in one flask from inexpensive, commercially available starting materials. The pyrrolizidine products contain a variety of substitution patterns and as many as six stereogenic centers.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical science
دوره 4 2 شماره
صفحات -
تاریخ انتشار 2012